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Anti-BCL-2 Alpha antibody, Rabbit monoclonal

产品编号:3347563
规格:clone SP66, recombinant, expressed in proprietary host, affinity isolated antibody
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3347563100 μL4660
基本信息
NACRES
NA.41
General description【一般描述】
B-cell lymphoma 2 (BCL-2) is an anti-apoptotic and target gene of nuclear factor-κB (NF-κB). The protein is expressed in the nuclear envelope, mitochondria and endoplasmic reticulum. The gene encoding BCL-2 is localized on human chromosome 18q21.
Immunogen【免疫原】
Synthetic peptide corresponding to N-terminus of human BCL-2 alpha protein.
Biochem/physiol Actions【生化/生理作用】
B-cell lymphoma 2 (BCL-2) inhibits apoptosis in cells and has been shown to be upregulated in adenomas. Expression of BCL-2α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2α protein, whereas the normal or hyperplastic germinal centers are negative.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
recombinant【重组】
expressed in proprietary host
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
SP66, monoclonal
species reactivity
human (tested)
technique(s)
flow cytometry: 1:100
immunohistochemistry: 1:100
isotype【同位素/亚型】
IgG
UniProt accession no.【UniProt登记号】
P10415
shipped in【运输】
wet ice
storage temp.【储存温度】
2-8℃
Gene Information
human ... BCL2(596)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
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