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Anti-BCL2 (Ab-56) antibody produced in rabbit
产品别名
Anti-BCL2 (Ab-56) antibody produced in rabbit
Anti-B-cell CLL / lymphoma 2 antibody produced in rabbit
Anti-BCL-2 antibody produced in rabbit
基本信息
| MDL number | MFCD00239644 |
| NACRES | NA.41 |
| General description【一般描述】 | BCL2 (B-cell lymphoma 2) consists of pro- and antiapoptotic functions. It belongs to BCL2 family of proteins. It is mapped to chromosome 18q21.3 . |
| Immunogen【免疫原】 | Peptide sequence around aa. 54-58 (G-H-T-P-H), according to the protein BCL2. |
| Application【应用】 | Anti-BCL2 (Ab-56) antibody has been used in western blotting . |
| Biochem/physiol Actions【生化/生理作用】 | Overexpression of BCL2 (B-cell lymphoma 2) results in poor clinical predictions in diffuse large B-cell lymphoma (DLBCL). It plays an important role in the growth and progression of cancer. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~26 kDa |
| species reactivity | human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (G-H-T-P-H) |
| NCBI accession no.【NCBI登记号】 | NP_000624.2 |
| UniProt accession no.【UniProt登记号】 | P10415 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... BCL2(596) |
产品说明
| Target description【目标描述】 | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
