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Anti-BCL2L1 antibody produced in rabbit

产品编号:3347599
规格:IgG fraction of antiserum
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3347599100 μL3310
产品别名

Anti-BCL2L1 antibody produced in rabbit

Anti-BCLX

Anti-Bcl-xL

Anti-DKFZp781P2092

Anti-BCL2-like 1

Anti-BCL2L

Anti-Bcl-xS

Anti-BCL-XL/S

Anti-Bcl-X

基本信息
MDL number
MFCD00675212
NACRES
NA.41
General description【一般描述】
BCL2L1 is a signaling molecule that is known to regulate neuronal apoptosis. Furthermore, BCL2L1 can facilitate the survival of retinal ganglion cells.
Rabbit Anti-BCL2L1 associates with rabbit, rat, bovine, canine, pig, mouse, and human BCL2L1.
Immunogen【免疫原】
Synthetic peptide directed towards the N terminal region of human BCL2L1
Application【应用】
Rabbit Anti-BCL2L1 antibody can be used for western blot (2.5μg/ml) assays.
Biochem/physiol Actions【生化/生理作用】
BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Sequence【序列】
Synthetic peptide located within the following region: SNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAING
Physical form【外形】
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
IgG fraction of antiserum
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
26 kDa
species reactivity
human, pig, dog, bovine, sheep, rabbit, horse
concentration【浓度】
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_612815
UniProt accession no.【UniProt登记号】
Q07817
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... BCL2L1(598)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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