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Anti-BIRC7 (C-term) antibody produced in rabbit
产品编号: | 3347888 |
规格: | IgG fraction of antiserum, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-BIRC7 (C-term) antibody produced in rabbit
Anti-Kidney inhibitor of apoptosis protein
Anti-ML-IAP
Anti-KIAP
Anti-Baculoviral IAP repeat-containing protein 7
Melanoma inhibitor of apoptosis protein
基本信息
NACRES | NA.41 |
General description【一般描述】 | BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. |
Immunogen【免疫原】 | BIRC7 (Q96CA5-2, 257-290) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BIRC7. |
Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | human |
technique(s) | immunohistochemistry: 1:50-1:100 indirect ELISA: 1:1000 western blot: 1:100-1:500 |
NCBI accession no.【NCBI登记号】 | NP_647478 |
UniProt accession no.【UniProt登记号】 | Q96CA5-2 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... BIRC7(79444) |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |