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ANTI-BRAF antibody produced in mouse

产品编号:3348164
规格:clone 4G7, purified immunoglobulin, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3348164100 μG5040
产品别名

ANTI-BRAF antibody produced in mouse

BRAF

BRAF1

MGC126806

B-RAF1

FLJ95109

基本信息
NACRES
NA.41
General description【一般描述】
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. (provided by RefSeq)
Immunogen【免疫原】
BRAF (NP_004324, 138 a.a. ~ 231 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
FQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVP
Physical form【外形】
Solution in phosphate buffered saline, pH 7.4
产品性质
biological source【生物来源】
mouse
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
4G7, monoclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen 35.97 kDa
species reactivity
human
technique(s)
indirect ELISA: suitable
western blot: 1-5 μg/mL
isotype【同位素/亚型】
IgG2bκ
NCBI accession no.【NCBI登记号】
NM_004333
UniProt accession no.【UniProt登记号】
P15056
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... BRAF(673)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
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