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Anti-CaM Kinase IV (CaMKIV) (AY-18) antibody produced in rabbit
| 产品编号： | 3350689 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 0.2 ML |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD01633080 |
| General description【一般描述】 | CaM Kinase IV is a Ca2+/calmodulin-dependent kinase that belongs to serine/threonine protein kinases family. CaM Kinase IV is expressed in the brain and thymus and is localized in cellular cytoplasm and nucleus. It facilitates the phosphorylation of several substrates in brain like-synapsin I, microtubule associated protein (MAP2), tau and tyrosine hydroxylase. Anti-caM kinase IV (CaMKIV) (AY-18) antibody can be used in western blotting (diluted 1:1000 and 1: 20,000) using human T-cell leukemia Jurkat whole cell extract and rat brain extract. It can also be used in microarray. Rabbit anti-caM kinase IV (CaMKIV) (AY-18) antibody reacts specifically with CaMKIV of rat but cross reacts with human CaMKIV. |
| Immunogen【免疫原】 | Peptide corresponding to amino acids 457-474 of rat CaM kinase IV conjugated to KLH. This sequence has extensive homology to mouse (80%) and human (70%) CaMKIV. |
| Application【应用】 | Anti-caM kinase IV (CaMKIV) (AY-18) antibody (diluted 1:500) can be used as a primary antibody in immunohistochemical studies. It can also be used in immunoblotting to detect and localize CAMKIV (65 kDa). |
| Physical form【外形】 | 0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。 |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 65 kDa |
| species reactivity | mouse, human, rat |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10,000 using sections of rat cerebellum microarray: suitable western blot: 1:20,000-1:1,000 using rat brain extract and Jurkat, whole cell extract, respectively |
| UniProt accession no.【UniProt登记号】 | Q16566 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CAMK4(814) mouse ... Camk4(12326) rat ... Camk4(25050) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
