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Anti-CBX3 antibody produced in rabbit
产品别名
Anti-CBX3 antibody produced in rabbit
Anti-Chromobox homolog 3 (HP1 γ homolog, Drosophila)
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | CBX3 is a chromobox homolog protein that interacts with H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of UV-induced- or double strand break-DNA damages. It modulates cotranscriptional RNA processing. Rabbit Anti-CBX3 antibody human, mouse, rat, bovine, canine, and chicken CBX3. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human CBX3 |
| Application【应用】 | Rabbit Anti-CBX3 antibody is suitable for western blot applications at a concentration of 0.25 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. CBX3 binds DNA and is a component of heterochromatin. CBX3 also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of CBX3 may explain the association of heterochromatin with the inner nuclear membrane.At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5′ UTR, have been found for this gene. |
| Sequence【序列】 | Synthetic peptide located within the following region: WEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDA |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 21 kDa |
| species reactivity | horse, rabbit, dog, bovine, guinea pig, mouse, rat, human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_009207 |
| UniProt accession no.【UniProt登记号】 | Q13185 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CBX3(11335) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
