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Anti-CEACAM5 antibody produced in chicken
| 产品编号： | 3352786 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品性质
| biological source【生物来源】 | chicken |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| manufacturer/tradename | Genway 15-288-22478 |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_004354.1 |
| UniProt accession no.【UniProt登记号】 | P06731 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CEACAM5(1048) |
基本信息
| General description【一般描述】 | CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) is a member of the CEACAM receptors, which in turn belong to immunoglobulin (Ig) superfamily. Its N-terminal contains an Ig variable-region-like domain, which is succeeded by multiple Ig constant-region-like domains. The latter domains protrude into the exoplasmic space. It is expressed by the squamous epithelial cells of the female genital tract. |
| Immunogen【免疫原】 | Immunogen Sequence: GI # 11386171, sequence 460-600 Recombinant carcinoembryonic antigen-related cell adhesion molecule 5 |
| Application【应用】 | Anti-CEACAM5 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. |
| Biochem/physiol Actions【生化/生理作用】 | Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5 OR CEA) is expressed by cancer cells. It is considered as an independent tumor marker in monitoring metastatic colorectal cancer and can be detected in the blood serum. CEA acts as a prognostic marker for malignant diseases (such as early-stage non-small cell lung cancer (NSCLC)). Increase in serum CEA may be attributed to the presence of local inflammation in the lung. CEA level may be a suitable biomarker for predicting tumor response. |
| Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
