抗 CKMT1(长期) 兔抗

NA.41

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.

CKMT1 (60-94)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CKMT1.

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

rabbit

unconjugated

IgG fraction of antiserum

primary antibodies

polyclonal

buffered aqueous solution

human, mouse

indirect ELISA: 1:1000
western blot: 1:100-1:500

NP_066270

P12532

dry ice

−20℃

human ... CKMT1(1159)

12 - Non Combustible Liquids

nwg