抗 冠状病毒-1C(C 端) 兔抗

NA.41

Coronin-1C (also known as CORO1C, Coronin-3, HCRNN4) belongs to the coronin family of tryptophan-aspartic acid (WD) 40 repeat-containing proteins. Coronin-1C is ubiquitously expressed and co-localizes with F-actin. In fibroblasts, CORO1C is localized both in the cytosol and in the submembrane cytoskeleton, especially at lamellipodia and membrane ruffles.

Anti-Coronin-1C (C-terminal) antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

Coronins appear to function primarily in association with the membrane cytoskeleton through interaction with F-actin and the actin-related protein (Arp2/3) complex. They localize to submembrane areas and regulate cell motility and cytoskeletal rearrangement. important in cytokinesis, cell motility, endocytosis, axonal growth, wound healing and signal transduction by altering actin dynamics. Coronin-1C is abundantly expressed in the central nervous system (CNS) during embryogenesis and first postnatal stages and in primary oligodendrocytes.

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

rabbit

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

antigen ~55 kDa

antibody small pack of 25 μL

~1.5 mg/mL

indirect immunofluorescence: 5-10 μg/mL using NIH3T3 cells
western blot: 1.5-3.0 μg/mL using A431 cell extract

dry ice

−20℃

human ... CORO1C(23603)
mouse ... Coro1c(23790)
rat ... Coro1c(501841)

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12 - Non Combustible Liquids