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Anti-CPEB4 antibody produced in rabbit
产品别名
Anti-CPEB4 antibody produced in rabbit
Anti-Cytoplasmic polyadenylation element binding protein 4
Anti-KIAA1673
基本信息
NACRES | NA.41 |
General description【一般描述】 | Cytoplasmic polyadenylation element-binding protein 4 (CPEB4) is a sequence-specific binding protein that belongs to the CPEB family. It consists of two domains, an unstructured domain, and a RNA binding domain. CPEB4 is expressed in the spinal cord and brain. The CPEB4 gene is mapped on the human chromosome at 5q35.2. |
Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human CPEB4 |
Biochem/physiol Actions【生化/生理作用】 | Cytoplasmic polyadenylation element-binding protein 4 (CPEB4) plays a key role in translational control during tumor development and modulates various biological processes in tumor progression, including invasion, metastasis, tumor cell growth, and vascularization. It is involved in pathologic angiogenesis, terminal erythroid differentiation, and non-neuronal tissues for cancer progression. Overexpression of the CPEB4 gene is associated with pancreatic ductal adenocarcinoma and glioblastoma. |
Sequence【序列】 | Synthetic peptide located within the following region: DEILGSEKAKSQQQEQQDPLEKQQLSPSPGQEAGILPETEKAKSEENQGD |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 80 kDa |
species reactivity | mouse, dog, guinea pig, human, rat, rabbit |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
UniProt accession no.【UniProt登记号】 | Q17RY0 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CPEB4(80315) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |