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Anti-CRTH2 (GRP44) antibody produced in rabbit
| 产品编号： | 3355336 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-CRTH2 (GRP44) antibody produced in rabbit
Anti-Chemoattractant Receptor-homologous Molecule expressed on TH2 Cells
Anti-Putative G-Protein Coupled Receptor 44
基本信息
| MDL number | MFCD08064414 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | peptide corresponding to the human CRTH2 (GRP44) protein, near the C-terminus (amino acids 329-348). |
| Application【应用】 | Anti-CRTH2 (GRP44) antibody produced in rabbit is suitable for western blotting at a working dilution of 1:500-1:1,000 using CRTH2- transfected Jurkat cells. |
| Biochem/physiol Actions【生化/生理作用】 | CRTH2 (chemoattractant receptor-homologous molecule), is known as the putative G protein-coupled receptor (GP44), is expressed on T helper 2 (Th2) cells. It is also referred as DP2, DL1R and CD294. It′s a human protein and belongs to G protein-coupled leukocyte chemo attractant receptor family. It is not expressed on human amniocytes or myocytes. On activation of CRTH2, PGD(2) induces human osteoclast apoptosis and the apoptosis intrinsic pathway. CRTH2, CD4 and T cells all together may be involved in the pathogenesis of IgG4-related Lacrimal gland enlargement (LGE) causing Mikulicz′s disease (MD). |
| Physical form【外形】 | Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~43 kDa by calculation |
| species reactivity | rat, mouse, human |
| technique(s) | western blot: 1:500-1:1,000 using CRTH2-transfected Jurkat cells |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GPR44(11251) mouse ... Gpr44(14764) rat ... Gpr44(309212) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
