Anti-CTTN (Ab-421) antibody produced in rabbit

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

~85 kDa

mouse, human

1 mg/mL

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100

IgG

(P-I-Y-E-D)

NP_005222.2

Q14247

wet ice

−20℃

human ... CTTN(2017)

Peptide sequence around aa. 419-423 (P-I-Y-E-D), according to the protein CTTN.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Cortactin is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene.

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10 - Combustible liquids

WGK 1