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Anti-CXCR4 antibody produced in chicken
| 产品编号： | 3356016 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-CXCR4 antibody produced in chicken
Anti-C-X-C chemokine receptor type 4
基本信息
| MDL number | MFCD01092337 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | Recombinant chemokine (C-X-C motif) receptor 4 isoform b Immunogen Sequence: GI # 4503175, sequence 6-41 |
| Application【应用】 | Anti-CXCR4 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. |
| Biochem/physiol Actions【生化/生理作用】 | C-X-C chemokine receptor type 4 (CXCR-4) is a protein encoded by the CXCR4 gene in humans. It is expressed in various cell types and the mechanisms involved in the regulation of its expression are still unknown. CXCR4 is a cofactor for fusion and entry of T cell-tropic strains of HIV-1. It is a chemokine receptor that is overexpressed in certain cancer types and involved in migration toward distant organs. CXCR4 is associated with various functions such as embryo organogenesis, immunological functions and T lymphocyte trafficking. High CXCR4 expression can be helpful in predicting clear-cell renal cell carcinoma (ccRCC). It plays a vital role in modulating cell trafficking in hematopoietic stem cells and clonal B cells. CXCR4 plays an important role in biological processes, as well as in tumorigenesis and the progression of cancer, especially breast cancer. It is an efficient prognostic factor for breast cancer. |
| Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide. |
产品性质
| biological source【生物来源】 | chicken |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | mouse, rat, human |
| manufacturer/tradename | Genway 15-288-21075 |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_003458.1 |
| UniProt accession no.【UniProt登记号】 | P61073 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CXCR4(7852) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
