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Anti-DGAT2L4 antibody produced in rabbit
产品别名
Anti-DGAT2L4 antibody produced in rabbit
Anti-Diacylglycerol O-acyltransferase 2-like 4
Anti-AWAT2
Anti-DC4
Anti-MFAT
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 38 kDa |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q6E213 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... DGAT2L4(158835) |
基本信息
| General description【一般描述】 | Diacylglycerol acyl transferases 2 (DGAT2L4) also known as acyl-CoA wax alcohol acyltransferase 2 (AWAT2), is a human multifunctional O-acyltransferase (MFAT). It is commonly expressed in undifferentiated sebocytes. In the human chromosome, the gene is localized on Xq13.1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human DGAT2L4 |
| Biochem/physiol Actions【生化/生理作用】 | DGAT2L4 is acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. It has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. DGAT2L4 may also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters, however this activity is unclear in vivo. |
| Sequence【序列】 | Synthetic peptide located within the following region: GEPLPMPKIENPSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
