您的位置：首页 > 产品中心 > Anti-EFNB2 (Ab-330) antibody produced in rabbit
Anti-EFNB2 (Ab-330) antibody produced in rabbit
产品别名
Anti-EFNB2 (Ab-330) antibody produced in rabbit
Anti-EPLG5 antibody produced in rabbit
Anti-LERK5 antibody produced in rabbit
Anti-Htk-L antibody produced in rabbit
Anti-ephrin-B2 antibody produced in rabbit
Anti-HTKL antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | EFNB2 (ephrin B2) is a membrane-bound molecule , that is located on human chromosome 13q33. |
| Immunogen【免疫原】 | Peptide sequence around aa. 328-332 (N-I-Y-Y-K), according to the protein EFNB2. |
| Biochem/physiol Actions【生化/生理作用】 | EFNB2 (ephrin B2) regulates the development of arterial endothelial cell. It also modulates the movement and adherence of vascular smooth muscle cells and pericytes to the extending arterial endothelial cell tubes. Overexpression of EFNB2 results in low tumor stage and elevated expression of TrkA in neuroblastomas. It controls the growth of thymocyte and differentiation of peripheral T cell. It is required for interleukin-6 (IL-6) signaling. It also modulates the antiviral immune responses. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~37 kDa |
| species reactivity | rat, human, mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (N-I-Y-Y-K) |
| NCBI accession no.【NCBI登记号】 | NP_004084.1 |
| UniProt accession no.【UniProt登记号】 | P52799 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... EFNB2(1948) |
产品说明
| Target description【目标描述】 | Ephrin-B2 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a lycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
