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Anti-EFTUD2 antibody produced in rabbit

产品编号:3359322
规格:affinity isolated antibody
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3359322100 μG5040
产品别名

Anti-EFTUD2 antibody produced in rabbit

U5 snRNP- specific protein

Snrp116

116 kDa U5 small nuclear ribonucleoprotein component

KIAA0031

116 kDa

基本信息
NACRES
NA.41
General description【一般描述】
Anti-EFTUD2 Antibody detects endogenous levels of total EFTUD2 protein.
EFTUD2 (Elongation factor Tu GTP binding domain containing 2) is a member of the U5 small nuclear ribonucleoprotein particle (snRNP) located on chromosome region 17q21.31. It encodes a small GTPase (116kDa) component of the major spliceosome. It consists of a GTP-binding domain and several other conserved domains homologous to the translational elongation factor EF-2. Its N-terminal domain has an acidic domain.
Immunogen【免疫原】
The antiserum was produced against synthesized peptide derived from human EFTUD2.

Immunogen Range: 321-370
Application【应用】
Anti-EFTUD2 antibody produced in rabbit is suitable for immunohistochemistry and western blot.
Biochem/physiol Actions【生化/生理作用】
EFTUD2 (Elongation factor Tu GTP binding domain containing 2) acts as a component of the spliceosome complex during translocation of mRNA on the ribosome. It produces mature mRNAs by binding to GTP during the processing of precursor mRNAs. Haploinsufficient genetic mutation in EFTUD2 causes a sporadic malformation syndrome, mandibulofacial dysostosis with microcephaly (MFDM), characterized with severe craniofacial abnormalities, microcephaly, growth delay, hearing loss, cleft palate, choanal atresia and dysmorphic features.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form【外形】
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen 109 kDa
species reactivity
human, mouse
concentration【浓度】
~1 mg/mL
technique(s)
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.【NCBI登记号】
Q15029
UniProt accession no.【UniProt登记号】
Q15029
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... EFTUD2(9343)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
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