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Anti-ENO1 antibody produced in chicken

产品编号:3360005
规格:affinity isolated antibody, buffered aqueous solution
包装规格:50 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
336000550 μG4730
基本信息
NACRES
NA.41
General description【一般描述】
Enolase 1 (ENO1 or ENOα) is a type of enolase enzyme, which in mammals, has three different isoforms namely, α-, β- and γ-enolase. It is an essential cytoplasmic glycolytic enzyme, and has a molecular weight of 48kDa. An alternatively spliced form resides in the nucleus, which has a molecular weight of 37kDa.
Immunogen【免疫原】
Recombinant enolase 1
Immunogen Sequence: GI # 4503571, sequence 161-320
Application【应用】
Anti-ENO1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions【生化/生理作用】
Enolase 1(α-enolase) is a homodimer composed of 2 α subunits. ENO1 is involved in tumor progression and prognosis of human glioma. Overexpression of ENO1 is associated with progression of glioma while its knockdown leads to suppressed cell growth, migration and invasion progression by inactivating the PI3K/Akt pathway in glioma cells. The lower expression of ENO1 decreases the response to hypoxia and enhances the sensitivity of the cells to radiation therapy. It may act as a drug target for the treatment of breast cancer.
Physical form【外形】
Solution in phosphate buffered saline containing 0.02% sodium azide.
产品性质
biological source【生物来源】
chicken
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
mouse, human, rat
manufacturer/tradename
Genway 15-288-22683
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_001419.1
UniProt accession no.【UniProt登记号】
P06733
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... ENO1(2023)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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