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Anti-FLT3 antibody produced in rabbit
产品别名
Anti-FLT3 antibody produced in rabbit
Stem cell tyrosine kinase 1
CD135 antigen
STK-1
Tyrosine-protein kinase receptor FLT3
基本信息
| MDL number | MFCD01864666 |
| NACRES | NA.41 |
| General description【一般描述】 | Anti-FLT3 antibody detects endogenous levels of total FLT3 protein. FLT3 (Fms-like tyrosine kinase) is a member of tyrosine kinase (RTK) family. It has an extracellular domain consisting of five immunoglobulin-like domains and an intracellular kinase domain interrupted by a kinase insert. It is located on human chromosome 13q12. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human FLT3. Immunogen Range: 565-614 |
| Biochem/physiol Actions【生化/生理作用】 | Mutation in FLT3 (Fms-like tyrosine kinase) results in acute myeloid leukemia and it also induces warburg effect and offers therapeutic sensitivity to glycolytic inhibition. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 112 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P36888 |
| UniProt accession no.【UniProt登记号】 | P36888 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... FLT3(2322) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
