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Anti-GMPR2 antibody produced in rabbit
产品别名
Anti-GMPR2 antibody produced in rabbit
Anti-MGC15084
Anti-guanosine monophosphate reductase 2
Anti-MGC830
基本信息
NACRES | NA.41 |
General description【一般描述】 | Guanosine monophosphate reductase 2 (GMPR2) is known to promote monocytic differentiation in HL-60 leukemia cells. Lack of GMPR2 expression has been linked to basal phenotype and patient outcome in breast carcinomas. Rabbit Anti-GMPR2 antibody recognizes canine, bovine, human, mouse, rat, and zebrafish GMPR2. |
Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human GMPR2 |
Application【应用】 | Rabbit Anti-GMPR2 antibody is suitable for western blot applications at a concentration of 5 μg/ml. |
Biochem/physiol Actions【生化/生理作用】 | GMPR2 catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. It plays a role in modulating cellular differentiation. |
Sequence【序列】 | Synthetic peptide located within the following region: GAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGV |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 20 kDa |
species reactivity | human, horse, rabbit, mouse, dog |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_001002002 |
UniProt accession no.【UniProt登记号】 | Q9P2T1 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... GMPR2(51292) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |