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Anti-Gnb2l1 antibody produced in rabbit
产品别名
Anti-Gnb2l1 antibody produced in rabbit
Anti-Guanine nucleotide binding protein (G protein), β polypeptide 2-like 1
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 35 kDa |
| species reactivity | mouse, guinea pig, rabbit, rat, human, sheep, bovine, dog |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_006089 |
| UniProt accession no.【UniProt登记号】 | P63244 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GNB2L1(10399) |
基本信息
| General description【一般描述】 | Guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 (GNB2L1) is a stable housekeeping gene expressed in alveolar macrophage and neutrophils. The gene has been hypothesized to encode a protein RACK1 (Receptor for activated C kinase 1). It is mapped on the telomeric position of chromosome 5q35.3. |
| Specificity【特异性】 | Anti-GNB2L1 polyclonal antibody reacts with canine, human, mouse, rat, pig, zebrafish, and chicken guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 proteins. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the C terminal region of human GNB2L1 |
| Application【应用】 | Anti-GNB2L1 polyclonal antibody is used to tag guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 protein for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the expression of guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 in macrophages and neutrophils. |
| Biochem/physiol Actions【生化/生理作用】 | Guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 (GNB2L1) is a scaffold protein highly involved in the binding and anchorage of protein kinase C. It has been hypothesized that GNB2L1 may act as a regulatory cofactor of multidrug resistance protein 3 (MDR3/ABCB4) and is vital for the plasma membrane localization and for mediating the translocation function of ABCB4. |
| Sequence【序列】 | Synthetic peptide located within the following region: LEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVW |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
