Anti-GPR39 antibody produced in rabbit

NA.41

GPR39 (G protein-coupled receptor 39) is an orphan member of the ghrelin receptor family expressed in brain and other peripheral tissues.
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.

Synthetic 20 amino acid peptide from C-terminus of human GPR39. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (95%); Marmoset (85%).

Anti-GPR39 antibody produced in rabbit is suitable for western blot at a concentration of 5μg/mL.

GPR39 (G protein-coupled receptor 39) exerts ligand-independent signaling activity. It is mainly involved in the regulation of growth hormone secretion. It facilitates the functional activities of the growth hormone-releasing peptides (GHRPs) and non-peptide ligands such as L-692,429 and MK-0677. It has been studied that zinc ion triggers GPR39 activity during food intake and energy metabolism. Study also shows that GPR39 may control the neuronal activity not only by altering transmitter expression and release but also through altering neuronal plasticity.

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Supplied at 1 mg/ml
Solution in phosphate-buffered saline containing less than 0.1% sodium azide.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human

immunohistochemistry: 5 μg/mL

O43194

dry ice

−20℃

human ... GPR39(2863)

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