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Anti-GRIN2B (Ab-1474) antibody produced in rabbit
产品别名
Anti-GRIN2B (Ab-1474) antibody produced in rabbit
Anti-glutamate receptor, ionotropic, N-methyl D-aspartate 2B antibody produced in rabbit
Anti-NMDAR2B antibody produced in rabbit
Anti-NR2B antibody produced in rabbit
Anti-MGC142180 antibody produced in rabbit
Anti-MGC142178 antibody produced in rabbit
基本信息
| MDL number | MFCD00243314 |
| NACRES | NA.41 |
| General description【一般描述】 | GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) codes for N-methyl d-aspartate receptor subtype 2B (GluN2B). It belongs to the N-methyl-D-aspartate receptor (NMDAR) gene family. It is located on human chromosome 12p13.1. |
| Immunogen【免疫原】 | Peptide sequence around aa. 1472-1476 (H-V-Y-E-K), according to the protein GRIN2B. |
| Biochem/physiol Actions【生化/生理作用】 | GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) plays an important role in the growth of neurons and is highly essential for the learning and memory. GRIN2B mutation is associated with neuropsychiatric and developmental disorders like schizophrenia, Parkinson′s disease and bipolar disorder. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~190 kDa |
| species reactivity | mouse, rat, human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (H-V-Y-E-K) |
| NCBI accession no.【NCBI登记号】 | NP_000825.2 |
| UniProt accession no.【UniProt登记号】 | Q13224 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... GRIN2B(2904) |
产品说明
| Target description【目标描述】 | NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
