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Anti-GRP78 antibody produced in rabbit
产品别名
Anti-GRP78 antibody produced in rabbit
Heat shock 70 kDa protein 5
Immunoglobulin heavy chain-binding protein
BIP
GRP-78
78 kDa glucose-regulated protein
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The molecular weight of GRP78 is 78kDa. Glucose/regulated protein 78 (GRP78) is a stress-associated protein. It is mapped to human chromosome 9q33.3. It is also known as HSPA5 (heat shock 70kDa protein 5) and immunoglobulin heavy chain binding protein (BiP). It is present in nucleated cells like thyroid, lung, smooth muscle, liver and several cells of the immune system. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human GRP78. Immunogen Range: 605-654 |
| Biochem/physiol Actions【生化/生理作用】 | Glucose/regulated protein 78 (GRP78) participates in stress-associated diseases. It also participates in protein biogenesis (protein transport into the endoplasmic reticulum (ER), protein folding and assembly and ER associated protein degradation), signal transduction and calcium homeostasis. GRP78 levels are elevated during various human cancers and tumors. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 72 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:5000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P11021 |
| UniProt accession no.【UniProt登记号】 | P11021 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... HSPA5(3309) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
