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Anti-HMOF/MYST1 (C-term) antibody produced in rabbit
| 产品编号： | 3367913 |
| 规格： | saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-HMOF/MYST1 (C-term) antibody produced in rabbit
Anti-MYST1
Anti-Probable histone acetyltransferase MYST1
Anti-HMOF
Anti-MYST protein 1
Anti-MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3; MIM 601408), yeast YBF2 and SAS2, and TIP60 (HTATIP; MIM 601409). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin (Neal et al., 2000 [PubMed 10786633]).[supplied by OMIM]. MYST histone acetyltransferase 1 (MYST1), also known as human males absent on the first (HMOF), is encoded by the gene mapped to human chromosome 16p11.2. The encoded protein belongs to MYST family of histone acetyltransferases (HATs). MYST1 contains N-terminal chromodomain, involved in binding noncoding RNA and a central MYST histone acetyltransferase domain. |
| Immunogen【免疫原】 | HMOF/MYST1 (NP_115564, 414-449) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the C-term of human HMOF/MYST1. |
| Biochem/physiol Actions【生化/生理作用】 | MYST histone acetyltransferase 1 (MYST1) catalyzes the acetylation of Lys16 residue in histone H4. It also plays a vital role in various cellular processes, such as gene transcription, cell proliferation, differentiation and DNA repair response. MYST1 is essential for maintaining normal chromatin architecture of all cells of early male and female embryos.Aberrations in the gene expression leads to certain type of primary cancers. |
| Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: 1:50-1:100 indirect ELISA: 1:1000 western blot: 1:100-1:500 |
| NCBI accession no.【NCBI登记号】 | NP_115564 |
| UniProt accession no.【UniProt登记号】 | Q9H7Z6 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MYST1(84148) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
