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Anti-HSP90AB1 (Ab-254) antibody produced in rabbit
产品别名
Anti-HSP90AB1 (Ab-254) antibody produced in rabbit
Anti-D6S182 antibody produced in rabbit
Anti-FLJ26984 antibody produced in rabbit
Anti-HSP90-BETA antibody produced in rabbit
Anti-HSP90B antibody produced in rabbit
Anti-heat shock protein 90kDa alpha (cytosolic), class B member 1 antibody produced in rabbit
基本信息
| MDL number | MFCD07370344 |
| NACRES | NA.41 |
| General description【一般描述】 | HSP90AB1 (heat shock protein 90 αfamily class B member 1) belongs to the Hsp90 family. It consists of major members-Hsp90α, Hsp90β, GRP94 (glucose-regulated protein 94) and Hsp75. It is located on chromosome 6p21. It is an ATP-dependent molecular chaperone, that is of 90kDa. |
| Immunogen【免疫原】 | Peptide sequence around aa. 252-256 (V-G-S-D-E), according to the protein HSP90AB1. |
| Biochem/physiol Actions【生化/生理作用】 | HSP90AB1 (heat shock protein 90 αfamily class B member 1) participates in signal transduction, protein folding and degradation, and morphological evolution. It is required for the transport of client proteins between the cytoplasm and nucleus. In lung adenocarcinoma patients, overexpression of HSP90AB1 in non-small cell lung cancer tissues results in imperfect clinical predictions. Suppression of this gene reduces the potential of endothelial cells to form tube structures. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~92 kDa |
| species reactivity | rat, mouse, human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (V-G-S-D-E) |
| NCBI accession no.【NCBI登记号】 | NP_031381.2 |
| UniProt accession no.【UniProt登记号】 | P08238 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... HSP90AB1(3326) |
产品说明
| Target description【目标描述】 | Molecular chaperone. Has ATPase activity. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
