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Anti-Keratin 15 antibody produced in rabbit
产品别名
Anti-Keratin 15 antibody produced in rabbit
CK-15
Keratin type I cytoskeletal 15
Cytokeratin-15
K15
基本信息
NACRES | NA.41 |
General description【一般描述】 | Keratin 15 (KRT15)/cytokeratin 15, a type I keratin, belongs to the keratin (KRT) gene family. It is expressed in basal keratinocytes of stratified epithelium. KRT15 gene is located on human chromosome 17q21.2. Anti-Keratin 15 antibody detects endogenous levels of total Keratin 15 protein. Anti-Keratin 15 Antibody detects endogenous levels of total Keratin 15 protein. |
Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Keratin 15. Immunogen Range: 1-50 |
Application【应用】 | Anti-Keratin 15 antibody produced in rabbit has been used in: immunohistochemistry (1:100), immunofluorescence (1:100), immunostaining |
Biochem/physiol Actions【生化/生理作用】 | Keratin 15 (KRT15) participates in maintaining cytoplasmic stability. It acts as a marker for skin stem cells in the hair follicle bulge. KRT15 plays a major role in epidermal homeostasis. It is associated with tumorigenesis. KRT15 might serve as a biomarker in predicting the prognosis of breast invasive carcinoma (BRCA) patients. Overexpression of the KRT15 gene is seen in squamous-cell carcinoma. |
Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen 49 kDa |
species reactivity | human, rat, mouse |
concentration【浓度】 | ~1 mg/mL |
technique(s) | ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
NCBI accession no.【NCBI登记号】 | P19012 |
UniProt accession no.【UniProt登记号】 | P19012 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... KRT15(3866) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |