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ANTI-LC3 (APG8A) antibody produced in rabbit
产品编号: | 3372977 |
规格: | IgG fraction of antiserum, buffered aqueous solution |
包装规格: | 400 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
ANTI-LC3 (APG8A) antibody produced in rabbit
Autophagy-related protein LC3 A
Microtubule-associated proteins 1A/1B light chain 3A
MAP1 light chain 3-like protein 1
MAP1LC3A
Autophagy-related ubiquitin-like modifier LC3 A
基本信息
NACRES | NA.41 |
General description【一般描述】 | The gene autophagy-related protein 8A (APG8A), also referred to as MAP1LC3A (microtubule associated protein 1 light chain 3 α), is a homologue of Apg8p necessary for autophagy in yeast. The cytosolic form of the protein, upon processing, gets localized to the autophagosome membranes. The LC3 gene is mapped to human chromosome 20q11.22. |
Biochem/physiol Actions【生化/生理作用】 | The gene MAP1LC3A (microtubule associated protein 1 light chain 3 α) or LC3 or autophagy-related protein 8A (APG8A) encodes a protein that serves as a marker of autophagosomes. It is found to be expressed on surviving oligodendrocytes in Nasu-Hakola disease brains and may be involved in the induction of oligodendrogliopathy. |
Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 14272 Da |
species reactivity | human |
technique(s) | immunofluorescence: 1:200 western blot: 1:1000 |
NCBI accession no.【NCBI登记号】 | NP_115903.1 |
UniProt accession no.【UniProt登记号】 | Q9H492 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MAP1LC3A(84557) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |