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Anti-Leukemia Inhibitory Factor antibody produced in goat

产品编号:3373239
规格:affinity isolated antibody, lyophilized powder
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3373239100 μG7130
产品别名

Anti-Leukemia Inhibitory Factor antibody produced in goat

Emfilermin

D factor

LIF

CDF

differentiation inhibitory activity

DIA

基本信息
MDL number
MFCD00283185
NACRES
NA.41
General description【一般描述】
Leukemia inhibitory factor (LIF) is a pleotropic glycoprotein that belongs to the IL6 family of cytokines. It is secreted by many cell types such as, fibroblasts, macrophages, T cells, monocytes, liver cells, osteoblasts and cells of endometrium. LIF interacts with a heterodimeric receptor composed of two subunits, gp130 and gp190. A variety of signal transduction pathways are triggered in response to LIF including ERK/MAPK, JAK1, PI3K, STAT3, Jun-cFos and NF-κB. The various functions of LIF include proliferation of adult human T cells, maintenance of pluripotency of embryonic stem cells and inhibition of leukemic ell differentiation. Reports also indicate the important role of LIF in lactation, tissue regeneration after brain and spinal cord injury, muscle regeneration and motor neuron functions.
Anti-Leukemia Inhibitory Factor recognizes mouse leukemia inhibitory factor. It shows less than 5% cross-reactivity with recombinant human LIF.
Immunogen【免疫原】
purified, E. coli-derived recombinant mouse leukemia inhibitory factor.
Application【应用】
Anti-Leukemia Inhibitory Factor may be used in neutralization reactions at a working concentration of 0.5 ng/ml. For immunoblotting a concentration of 0.1-0.2 μg/ml is recommended.
Physical form【外形】
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
goat
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
lyophilized powder
species reactivity
mouse
technique(s)
neutralization: suitable
western blot: 0.1-0.2 μg/mL
UniProt accession no.【UniProt登记号】
P09056
storage temp.【储存温度】
−20℃
Gene Information
mouse ... Lif(16878)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 1
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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