广州伟伯科技有限公司
您的位置:首页 > 产品中心 > Anti-LRP3 (C-term) antibody produced in rabbit
产品搜索:

Anti-LRP3 (C-term) antibody produced in rabbit

产品编号:3374135
规格:IgG fraction of antiserum, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3374135100 μG5040
产品别名

Anti-LRP3 (C-term) antibody produced in rabbit

Anti-Low density lipoprotein receptor-related protein 3

基本信息
NACRES
NA.41
General description【一般描述】
Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration (1). Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes (2). All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family (3).
Immunogen【免疫原】
LRP3 (666-703)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human LRP3.
Physical form【外形】
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
IgG fraction of antiserum
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
human
technique(s)
immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
NCBI accession no.【NCBI登记号】
NP_002324
UniProt accession no.【UniProt登记号】
O75074
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... LRP3(4037)
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
nwg
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.7581