Anti-MAPT (Ab-231) antibody produced in rabbit

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

~48 kDa
~62 kDa
~78 kDa

mouse, rat, human

1 mg/mL

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

IgG

(V-R-T-P-P)

NP_001116538.1

P10636

wet ice

−20℃

human ... MAPT(4137)

Peptide sequence around aa. 229-233 (V-R-T-P-P), according to the protein MAPT.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

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12 - Non Combustible Liquids

WGK 1