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Anti-Matrix Metalloproteinase-14, N-Terminal antibody produced in rabbit
产品编号: | 3375588 |
规格: | 0.5 mg/mL, affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Matrix Metalloproteinase-14, N-Terminal antibody produced in rabbit
Anti-MMP-14
基本信息
MDL number | MFCD03097005 |
NACRES | NA.41 |
General description【一般描述】 | Matrix metalloproteinase-14 (MMP-14) is a collagenase localized to the cell membrane. The gene encoding it is present on human chromosome 14. |
Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 185-299 in the N-terminal region of human matrix metalloproteinase-14 (membrane-type matrix metalloproteinase-1), conjugated to KLH. |
Application【应用】 | Anti-matrix metalloproteinase-14, N-terminal antibody produced in rabbit has been used for western blotting at a dilution of 1:100. |
Biochem/physiol Actions【生化/生理作用】 | Matrix metalloproteinase-14 (MMP-14) aids in the migration of leukocytes and breaks down collagen. Migration of cells through the extracellular matrix is also mediated by it. MMP-14 has been shown to be associated with tuberculosis and glioma. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.09% (w/v) sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~65 kDa |
species reactivity | human |
concentration【浓度】 | 0.5 mg/mL |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 using human cancer tissue indirect ELISA: 1:1,000 western blot: 1:100-1:500 using A375 lysate |
UniProt accession no.【UniProt登记号】 | P50281 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MMP14(4323) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |