Anti-Matrix Metalloproteinase-24, Cytoplasmic antibody produced in rabbit

MFCD03097030

NA.41

Matrix metalloproteinase-24 (MMP-24) is mainly expressed in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20.

Reacts with native and reduced MMP-24. The antibody recognizes the pro-form of MMP-24 as well as activation/breakdown products. The cytoplasmic domain of MMP-24 is detached when MT-MMPs shed from themselves, thus this antibody should not detect this form of MMP-24.

synthetic peptide corresponding to the cytoplasmic domain of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5)

Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer.

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous glycerol solution

antigen 65 kDa

human, mouse

~1 mg/mL

flow cytometry: suitable
immunohistochemistry (frozen sections): suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 1:2,000

Q9Y5R2

wet ice

−20℃

human ... MMP24(10893)
mouse ... Mmp24(17391)

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.