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抗-基质金属蛋白酶 28,前肽区 兔抗
Anti-Matrix Metalloproteinase-28, Propeptide Region antibody produced in rabbit
产品编号: | 3375621 |
规格: | ~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
抗-基质金属蛋白酶 28,前肽区 兔抗
Anti-Matrix Metalloproteinase-28, Propeptide Region antibody produced in rabbit
Anti-MMP-28
Anti-Epilysin
基本信息
MDL number | MFCD04040453 |
NACRES | NA.41 |
General description【一般描述】 | Matrix metalloproteinase-28 (MMP-28) is expressed in normal tissues like the epidermis of the skin, brain, lungs and intestine. It possesses an activation sequence and a pro-domain. The gene encoding it is localized on human chromosome 17q11.2 and has eight exons. |
Specificity【特异性】 | By immunoblotting against the reduced protein, the antibody identifies bands at 62 kDa and 58 kDa, as well as breakdown products at 50 kDa, 48 kDa, and 46 kDa. At higher antibody concentrations, the antibody also detects a 70 kDa band in rat and mouse tissues. |
Immunogen【免疫原】 | synthetic peptide corresponding to the propeptide region of human matrix metalloproteinase-28. |
Biochem/physiol Actions【生化/生理作用】 | Matrix metalloproteinase-28 (MMP-28) may have a role in modulating matrix composition. It is an endopeptidase which degrades casein and mediates epithelial to mesenchymal transition. MMP-28 aids in progression of tumors and is overexpressed in gastric carcinomas. |
Physical form【外形】 | Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 200 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous glycerol solution |
species reactivity | human |
concentration【浓度】 | ~1 mg/mL |
technique(s) | western blot: 1:1,000 |
UniProt accession no.【UniProt登记号】 | Q9H239 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MMP28(79148) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |