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Anti-METTL1 antibody produced in rabbit
产品别名
Anti-METTL1 antibody produced in rabbit
Anti-Methyltransferase like 1
Anti-C12orf1
Anti-TRM8
Anti-YDL201w
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Anti-METTL1 antibody codes for methyltransferase like 1 that has an S-adenosylmethionine-binding motif. It is inactivated upon phosphorylation by PKB and RSK. A functional variant in METTL1, along with other genetic variants, has been associated with multiple sclerosis. Rabbit Anti-METTL1 antibody recognizes bovine, human, mouse, and rat METTL1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human METTL1 |
| Application【应用】 | Rabbit Anti-METTL1 antibody is suitable for western blot applications at a concentration of 2.5 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | METTL1 contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. |
| Sequence【序列】 | Synthetic peptide located within the following region: KGQLTKMFFLFPDPHFKRTKHKWRIISPTLLAEYAYVLRVGGLVYTITDV |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 34 kDa |
| species reactivity | bovine, rat, horse, rabbit, dog, goat, mouse, human, guinea pig |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_005362 |
| UniProt accession no.【UniProt登记号】 | Q9UBP6 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... METTL1(4234) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
