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Anti-MIER1 antibody produced in rabbit
产品别名
Anti-MIER1 antibody produced in rabbit
Anti-Mesoderm induction early response 1 homolog (Xenopus laevis)
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | MIER1 is a transcriptional regulator that may repress transcription by blocking the function of histone acetyltransferase. Rabbit Anti-MIER1 antibody recognizes zebrafish, rabbit, bovine, chicken, canine, human, mouse, and rat MIER1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human MIER1 |
| Application【应用】 | Rabbit Anti-MIER1 antibody can be used for western blot application at a concentration of 1.25 μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1). |
| Sequence【序列】 | Synthetic peptide located within the following region: RRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRF |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 49 kDa |
| species reactivity | rabbit, dog, guinea pig, mouse, horse, bovine, human, rat |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001071170 |
| UniProt accession no.【UniProt登记号】 | Q8NES5 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MIER1(57708) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
