Anti-MIMITIN antibody produced in rabbit

NA.41

Mimitin antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Mimitin.

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

The action of this antibody can be blocked using blocking peptide SBP3500112.

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human

immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable

NP_777549

Q8N183

dry ice

−20℃

human ... NDUFAF2(91942)

Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.

12 - Non Combustible Liquids

WGK 2