您的位置：首页 > 产品中心 > Anti-Monoamine Oxidase B 兔抗
Anti-Monoamine Oxidase B 兔抗
Anti-Monoamine Oxidase B antibody produced in rabbit
| 产品编号： | 3377181 |
| 规格： | ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Monoamine Oxidase B 兔抗
Anti-Monoamine Oxidase B antibody produced in rabbit
Anti-MAO, brain
Anti-MAO, platelet
Anti-Adrenalin oxidase
Anti-Tyramine oxidase
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Monoamine Oxidase B (MAO-B) is a mitochondrial flavo enzyme. It is mainly found in the brain in dopaminergic, serotonergic, and histaminergic neurons and astrocytes. Monoamine Oxidase B is encoded by the gene mapped to human chromosome Xp11.3. |
| Specificity【特异性】 | Anti-Monoamine Oxidase B specifically recognizes human, mouse, and rat MAO-B. |
| Application【应用】 | Anti-Monoamine Oxidase B antibody has been used in western blotting. Anti-Monoamine Oxidase B antibody produced in rabbit has also been used in coimmunoprecipitation (co-IP) and immunohistochemistry. |
| Biochem/physiol Actions【生化/生理作用】 | Monoamine oxidase B (MAO-B) is considered the predominant isoform responsible for dopamine metabolism in the human central nervous system (CNS). MAO-B activity correlates with personality traits. Alterations in MAO-B activity may underlie dopamine pathobiology in major depression. Selective MAO-B inhibitors elevate synaptosomal dopamine concentrations, and have recently shown clinical efficacy in the treatment of early Parkinson′s disease. |
| Physical form【外形】 | 0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。 |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~58 kDa |
| species reactivity | mouse, human, rat |
| concentration【浓度】 | ~1.5 mg/mL |
| technique(s) | western blot: 0.5-1.0 μg/mL using rat liver mitochondrial fraction |
| UniProt accession no.【UniProt登记号】 | P27338 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ASCC3(10973), MAOB(4129) rat ... Maob(25750) |
产品说明
| Storage and Stability【储存及稳定性】 | For continuous use, store at 2–8 ℃ for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
