您的位置：首页 > 产品中心 > Anti-Nanog antibody produced in rabbit
Anti-Nanog antibody produced in rabbit
产品别名
Anti-Nanog antibody produced in rabbit
Anti-Homeobox transcription factor Nanog
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The antibody detects endogenous level of total Nanog protein. |
| Immunogen【免疫原】 | Peptide sequence around aa. 137-141 (K-Q-V-K-T), according to the protein NP_079141.2 |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~42 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (K-Q-V-K-T) |
| NCBI accession no.【NCBI登记号】 | NM_024865.2 |
| UniProt accession no.【UniProt登记号】 | Q9H9S0 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... Nanog(79923) |
产品说明
| Target description【目标描述】 | Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes By similarity. Acts as a transcriptional activator or repressor By similarity. Binds optimally to the DNA consensus sequence 5′-TAAT[GT][GT]-3′ or 5′-[CG][GA][CG]C[GC]ATTAN[GC]-3′ By similarity. When overexpressed, promotes cells to enter into S phase and proliferation |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
