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Anti-NEUROD2 (AB1) antibody produced in rabbit

产品编号:3380064
规格:affinity isolated antibody
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3380064100 μL6300
产品别名

Anti-NEUROD2 (AB1) antibody produced in rabbit

Anti-Neurogenic differentiation 2

基本信息
NACRES
NA.41
Immunogen【免疫原】
Synthetic peptide directed towards the C terminal region of human NEUROD2
Biochem/physiol Actions【生化/生理作用】
NEUROD2 (Neurogenic differentiation 2) is a key transcription factor of the neuron-specific promoters such as GAP-43. It induces neurogenic differentiation by inhibiting RE1-Silencing Transcription Factor-mediated gene expression. NEUROD2 expression is critical for the development of amygdala, hippocampal mossy fiber synapses and for emotional learning.
NEUROD2 is a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of NEUROD2 can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.
Sequence【序列】
Synthetic peptide located within the following region: PGSRPTGHGLVFGSSAVRGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN
Physical form【外形】
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
41 kDa
species reactivity
rat, dog, mouse, rabbit, human, horse, guinea pig, bovine
concentration【浓度】
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_006151
UniProt accession no.【UniProt登记号】
Q15784
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... NEUROD2(4761)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
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