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Anti-PDPK1 antibody produced in rabbit
产品别名
Anti-PDPK1 antibody produced in rabbit
Anti-PkB-like
Anti-PRO0461
Anti-PkB-like1
Anti-MGC35290
Anti-MGC20087
Anti-3-Phosphoinositide dependent protein kinase-1
Anti-PDK1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | PDPK1 is a kinase that regulates several signaling pathways mediated by various hormones and growth factors. PDPK1 has been implicated in breast cancer metastasis and prostate cancer progression. Rabbit Anti-PDPK1 antibody recognizes human, mouse, rat, zebrafish, and pig PDPK1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human PDPK1 |
| Application【应用】 | Rabbit Anti-PDPK1 antibody has been used for western blot assays at a concentration of 0.5μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | PDPK1 phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. It may play a general role in signaling processes and in development. |
| Sequence【序列】 | Synthetic peptide located within the following region: IIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVS |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 63 kDa |
| species reactivity | guinea pig, bovine, mouse, human, dog, rabbit, rat, horse |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | XP_001715356 |
| UniProt accession no.【UniProt登记号】 | O15530 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PDPK1(5170) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
