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Anti-Phospho-APBB1-S347 antibody produced in rabbit
| 产品编号： | 3384095 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Phospho-APBB1-S347 antibody produced in rabbit
Anti-APBB1
Anti-Fe65 protein
Anti-FE65
Anti-Amyloid β A4 precursor protein-binding family B member 1
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | indirect ELISA: 1:1000 western blot: 1:100-1:500 |
| NCBI accession no.【NCBI登记号】 | NP_001155.1 |
| UniProt accession no.【UniProt登记号】 | O00213 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... APBB1(322) |
基本信息
| General description【一般描述】 | APBB1 is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer′s disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product′s nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer′s disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. |
| Immunogen【免疫原】 | APBB1 (NP_001155.1, ) This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S347 of human APBB1. |
| Physical form【外形】 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
