您的位置：首页 > 产品中心 > Anti-phospho-BLK (pTyr501) antibody produced in rabbit
Anti-phospho-BLK (pTyr501) antibody produced in rabbit
产品别名
Anti-phospho-BLK (pTyr501) antibody produced in rabbit
p55-Blk
Tyrosine-protein kinase BLK
B lymphocyte kinase
kinase Blk
EC 2.7.10.2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | B lymphoid tyrosine kinase (BLK) protein belongs to the Src kinase family. It has an Src homology 3 (SH3) and an Src homology 2 (SH2) domain N-terminal to the catalytic kinase domain. The BLK gene is located on human chromosome 8p23.1. |
| Specificity【特异性】 | The antibody detects endogenous levels of BLK only when phosphorylated at tyrosine 501. |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK. |
| Biochem/physiol Actions【生化/生理作用】 | B lymphoid tyrosine kinase (BLK) protein has oncogenic properties. It helps B-cell receptors transmit signals and may be important for B-cell repertoire development and mature B-cell activity. BLK participates in B-cell antigen receptor signaling. The BLK gene polymorphisms are linked to renal dysfunction in people with systemic lupus erythematosus. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 57 kDa |
| species reactivity | human |
| concentration【浓度】 | 1.0 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:100 |
| isotype【同位素/亚型】 | IgG |
| accession no.【登记号】 | NP_001706.2. |
| UniProt accession no.【UniProt登记号】 | P51451 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... BLK(640) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
