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Anti-phospho-MAPK14 (pTyr182) antibody produced in rabbit
产品别名
Anti-phospho-MAPK14 (pTyr182) antibody produced in rabbit
Anti-CSBP1 antibody produced in rabbit
Anti-CSPB1 antibody produced in rabbit
Anti-EXIP antibody produced in rabbit
Anti-CSBP2 antibody produced in rabbit
Anti-mitogen-activated protein kinase 14 antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of tyrosine 182 (T-G-Y(p)-V-A), according to the protein MAPK14. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~43 kDa |
| species reactivity | rat, human, mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (T-G-YP-V-A) |
| NCBI accession no.【NCBI登记号】 | NP_001306.1 |
| UniProt accession no.【UniProt登记号】 | Q16539 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... MAPK14(1432) |
产品说明
| Target description【目标描述】 | Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
