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Anti-phospho-PIK3R1 (pTyr467) antibody produced in rabbit
产品别名
Anti-phospho-PIK3R1 (pTyr467) antibody produced in rabbit
Anti-phosphoinositide-3-kinase, regulatory subunit 1 (alpha) antibody produced in rabbit
Anti-p85 antibody produced in rabbit
Anti-p85-ALPHA antibody produced in rabbit
Anti-GRB1 antibody produced in rabbit
基本信息
| MDL number | MFCD00282407 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y), according to the protein PIK3R1. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~85 kDa |
| species reactivity | mouse, rat, human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (L-YP-E-E-Y) |
| NCBI accession no.【NCBI登记号】 | NP_001107644.1 NP_005018.1 NP_852556.2 |
| UniProt accession no.【UniProt登记号】 | P27986 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PIK3R1(5295) |
产品说明
| Target description【目标描述】 | Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. /Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
