Anti-phospho-Pyk2 (pTyr⁴⁰²) antibody produced in rabbit

MFCD03455760

NA.44

Pyk2 (proline-rich kinase 2) is a protein that belongs to Tyr protein kinase family and is expressed in mesenchymal cells, epithelial cells, endothelial cells, neonatal cardiomyocytes, osteoclasts and neuronal cells. It has a crucial role in T and B cell antigen receptor signaling, cell cycle progression, metastasis, and NK cytotoxicity. It also modulates ion channel function and neuronal short- and long- term responses. Anti-phospho-Pyk2 (pTyr⁴⁰²) antibody can be used in western blotting (1:1,000). Rabbit anti-phospho-Pyk2 (pTyr⁴⁰²) antibody reacts specifically with Pyk2 (pTyr⁴⁰²) (116 kD approx.) of rat, chicken and human.

synthetic phosphopeptide derived from the region of Pyk 2 that contains tyrosine 402.

Anti-phospho-Pyk2 (pTyr⁴⁰²) antibody can be used in immunoblotting (diluted 1: 1000).

solution in Dulbecco′s phosphate buffered saline (without Mg²⁺ and Ca²⁺), pH 7.3, containing 50% glycerol, 1.0 mg/ml BSA (IgG and protease free) and 0.05% sodium azide.

rabbit

200

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous glycerol solution

antigen ~116 kDa

rat, human, chicken

western blot: 1:1,000 using chick embryo fibroblasts (CEF) cells expressing human Pyk2

Q14289

wet ice

−20℃

human ... PTK2B(2185)
rat ... Ptk2b(50646)

One vial is sufficient for 10 immunoblots.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.