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Anti-phospho-ZAP-70 (pTyr315) antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Zeta-chain-associated protein kinase 70 (ZAP70) is a tyrosine kinase, present in T cells and natural killer (NK) cells. It belongs to the spleen tyrosine kinase (Syk) family. This gene is mapped to human chromosome 2q11. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human ZAP-70 around the phosphorylation site of Tyr315. Immunogen Range: 281-330 |
| Biochem/physiol Actions【生化/生理作用】 | Zeta-chain-associated protein kinase 70 (ZAP70) plays an important role in T cell receptor (TCR) signaling. It acts as an adaptor protein to increase BCR (B-cell receptor) signaling. This protein is required for T-cell transendothelial migration mediated by C-X-C motif chemokine ligand 12. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 69 kDa |
| species reactivity | human, mouse, rat |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P43403 |
| UniProt accession no.【UniProt登记号】 | P43403 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ZAP70(7535) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
