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Anti-PRKCQ (Ab-695) antibody produced in rabbit
产品别名
Anti-PRKCQ (Ab-695) antibody produced in rabbit
Anti-nPKC-theta antibody produced in rabbit
Anti-MGC126514 antibody produced in rabbit
Anti-protein kinase C, theta antibody produced in rabbit
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Anti-PRKCT antibody produced in rabbit
基本信息
| NACRES | NA.41 |
| Immunogen【免疫原】 | Peptide sequence around aa. 693-697 (N-F-S-F-M), according to the protein PRKCQ. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~80 kDa |
| species reactivity | human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (N-F-S-F-M) |
| NCBI accession no.【NCBI登记号】 | NP_006248.1 |
| UniProt accession no.【UniProt登记号】 | Q04759 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PRKCQ(5588) |
产品说明
| Target description【目标描述】 | This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. Ref.8 PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
