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Anti-PRKD1 (Ab-910) antibody produced in rabbit
产品别名
Anti-PRKD1 (Ab-910) antibody produced in rabbit
Anti-PKC-MU antibody produced in rabbit
Anti-PKD antibody produced in rabbit
Anti-protein kinase D1 antibody produced in rabbit
Anti-PRKCM antibody produced in rabbit
Anti-PKCM antibody produced in rabbit
基本信息
| MDL number | MFCD03455823 |
| NACRES | NA.41 |
| General description【一般描述】 | PRKD1 gene encodes PKD1 (protein kinase D1), that belongs to the protein kinase D family. It is a serine/threonine kinase, which is expressed in cells of the normal mammary gland. The PRKD1 gene promoter has a great CpG island covering 1.2kb, including the transcription start site and the entire exon 1. |
| Immunogen【免疫原】 | Peptide sequence around aa. 908-912 (R-V-S-I-L), according to the protein PRKD1. |
| Biochem/physiol Actions【生化/生理作用】 | PRKD1 (Protein kinase D 1) is a negative modulator of cell migration . It plays an important role in cell adhesion, cell migration, vesicle transport, cell survival , signal transduction, membrane trafficking and immune function. It preserves the epithelial phenotype by inhibiting epithelial-to-mesenchymal transition. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | ~115 kDa |
| species reactivity | human, mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgG |
| immunogen sequence【免疫原序列】 | (R-V-S-I-L) |
| NCBI accession no.【NCBI登记号】 | NP_002733.2 |
| UniProt accession no.【UniProt登记号】 | Q15139 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PRKD1(5587) |
产品说明
| Target description【目标描述】 | Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
