Anti-S1P1 antibody produced in rabbit

MFCD02264095

NA.41

S1P1 (sphingosine-1-phosphate receptor 1) is one of the transmembrane G protein coupled receptor. It is a member of the endothelial differentiation gene (EDG) family of receptors, hence it is also known as endothelial differentiation gene (EDG-1). It is located on chromosome 1p21.

a 14 amino acid peptide near the carboxy-terminus of the human S1P1.

S1P1 (sphingosine-1-phosphate receptor 1) acts as an anti-apoptotic/pro-proliferative protein in AML (acute myeloid leukemia) cells. It participates in angiogenesis and lymphangiogenesis. It is considered as a pro-tumorigenic receptor, as it induces migration of cancer cell and invasion along with tumor neovascularization.

The action of this antibody can be blocked using blocking peptide SBP4809.

Solution in phosphate buffered saline containing 0.02% sodium azide

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

predicted mol wt 42 kDa

human, mouse, rat

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

P21453

dry ice

−20℃

human ... S1PR1(1901)

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12 - Non Combustible Liquids

WGK 2